Indian Journal of Nuclear Medicine
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Year : 2012  |  Volume : 27  |  Issue : 2  |  Page : 127-129

Lytic and sclerotic (mixed) vertebral metastasis in ganglioneuroblastoma

1 Department of Endocrinology, PGIMER, Chandigarh, India
2 Department of Nuclear Medicine, PGIMER, Chandigarh, India

Correspondence Address:
Sanjay Kumar Bhadada
Department of Endocrinology, PGIMER, Chandigarh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-3919.110721

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The clinical presentation of ganglioneuroblastoma is highly variable and it is not uncommon to see metastasis at presentation. Bone is the second most common site of metastasis in neuroblastoma. Neuroblastoma cells usually activate osteoclasts and form osteolytic lesions. Here, we describe a patient who presented with back pain. On evaluation, X-ray and positron emission tomography-computed tomography showed mixed lytic and sclerotic vertebral metastasis, and subsequently diagnosed as ganglioneuroblastoma.

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