Indian Journal of Nuclear Medicine
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Year : 2014  |  Volume : 29  |  Issue : 1  |  Page : 53-54

Leptomeningeal carcinomatosis as only pathological finding at FDG-PET/CT in case of tumor marker elevation in breast cancer

Department of Nuclear Medicine, Hospital Universitario "Infanta Cristina", Badajoz, Spain

Correspondence Address:
Maria Luz Dominguez Grande
Department of Nuclear Medicine, Hospital Universitario "Infanta Cristina", Badajoz
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-3919.125779

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Leptomeningeal carcinomatosis is an infrequent disease and although its treatment is palliative, earlier diagnosis will lead to prolonged survival and improve functional outcome. Whole-body FDG-PET allows the entire spinal cord to be examined noninvasively, so close attention should be paid to the spinal canal, since these lesions can easily be mistaken for physiologic uptake, sometimes there is no clinical suspicion and may occur without concurrent active cancer. We present a female patient with a history of carcinoma of the breast, who presented an elevation of serum tumor marker CA 15-3. An FDG-PET/CT study only revealed multiple abnormal uptake at the vertebral foramen at thoracic and lumbosacral regions suggesting leptomeningeal metastases that were confirmed by MRI and cerebrospinal fluid cytology.

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