Indian Journal of Nuclear Medicine
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Year : 2014  |  Volume : 29  |  Issue : 2  |  Page : 102-104

Malaria masquerading as relapse of Hodgkin's lymphoma on contrast enhanced 18 F-fluorodeoxyglucose positron emission tomography/computed tomography: A diagnostic dilemma

Department of Nuclear Medicine and PET-CT, Diwan Chand Satyapal Aggarwal Imaging and Research Center, New Delhi, India

Correspondence Address:
Sunil Jeph
Department of Nuclear Medicine and PET-CT, 10-B, K.G. Marg, New Delhi - 110 001
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-3919.130299

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18 Flurodeoxyglucose ( 18 F-FDG) positron emission tomography/computed tomography (PET/CT) is nowadays routinely used in management of lymphoma patients. We here present a case of Hodgkin's lymphoma which showed 18 F-FDG avid splenomegaly on PET/CT done for clinically suspected relapse. Further evaluation by peripheral smear examination revealed malaria. The patient was then started on anti-malarial medications and follow-up PET/CT revealed resolution of hypermetabolic splenomegaly. This report highlights that in endemic regions malaria can cause 18 F-FDG avid splenomegaly and might mimic relapse of lymphoma.

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