Indian Journal of Nuclear Medicine
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Year : 2014  |  Volume : 29  |  Issue : 4  |  Page : 262-263

Poor fluorodeoxyglucose uptake in myocardial viability study in nondiabetic Friedreich's ataxia patient

Department of Nuclear Medicine and PET-CT, Jaslok Hospital and Research Center, Mumbai, Maharashtra, India

Correspondence Address:
Sushanti Patil
405, Mahesh Darshan-2, Link Road, Kandarpada, Dahisar (W), Mumbai - 400 068, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-3919.142638

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A 48-year-old man, a known case of Friedreich's ataxia (FRDA) underwent cardiac fluorodeoxyglucose (FDG) positron emission tomography -computed tomography (PET/CT) for evaluation of myocardial viability. Tetrofosmin images showed an enlarged left ventricular cavity with small mid and basal inferior and apical infarct global hypokinesia with ejection fraction of 39%. Fluorodeoxyglucose images showed poor quality myocardial images. Friedreich's ataxia is associated with a high incidence of diabetes mellitus. Non-diabetic patients with Friedreich's ataxia have insulin resistance. This is associated with a reduction in the affinity of insulin receptors and membrane abnormality that alters the binding function of the insulin receptor.

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