Indian Journal of Nuclear Medicine
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Year : 2018  |  Volume : 33  |  Issue : 3  |  Page : 230-232

Silicone implant incompatibility syndrome: Mimicking metastases on fluoro-deoxy-glucose positron emission tomography–computed tomography in a treated case of carcinoma breast

1 Department of Nuclear Medicine and PET-CT, Apollo Hospitals, Chennai, Tamil Nadu, India
2 Department of Pathology, Apollo Hospitals, Chennai, Tamil Nadu, India

Correspondence Address:
Patel Asra
Department of Nuclear Medicine and PET-CT, Apollo Hospitals, Chennai No. 21, Greams Lane, Off Greams Road, Chennai - 600 006, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijnm.IJNM_29_18

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Silicone implant incompatibility syndrome (SIIS) has been identified as a cause of systemic symptoms such as lymphadenopathy, myalgia, and dyspnea in patients with silicone implants. We present a case of 76-year-old female patient, treated for carcinoma left breast with mastectomy and silicone breast implant, chemotherapy, and radiotherapy 42 years ago. There was a history of implant rupture and removal 2 years ago. The patient presented with right axillary swelling and dyspnea. 18-fluorine fluoro-deoxy-glucose positron emission tomography/computed tomography (F-18 FDG PET-CT) showed mildly FDG-avid left anterior chest wall and right rectus abdominis deposits, multiple lymph nodes, and low-grade FDG-avid pneumonitis changes in both lungs. Biopsy from the chest wall and rectus abdominis deposit was negative for malignancy and revealed foamy histiocytes and foreign-body giant cell reaction, indicative of SIIS. SIIS is a mimic for metastases and should be considered as a differential diagnosis in FDG PET-CT interpretation in patients with silicone breast implant.

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