| INTERESTING IMAGE |
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| Year : 2019 | Volume
: 34
| Issue : 4 | Page : 338-340 |
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Graves' ophthalmopathy on68Ga-DOTANOC positron emission tomography/computed tomography
Saurabh Arora1, Nishikant Avinash Damle1, Rachna Meel2, Kanak Lata1, Nikhil Tandon3, Sanjay Sharma4, Chandrasekhar Bal1
1 Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India
2 Department of Ophthalmology, All India Institute of Medical Sciences, New Delhi, India
3 Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India
4 Department of Radio-Diagnosis, All India Institute of Medical Sciences, New Delhi, India
Correspondence Address:
Dr. Nishikant Avinash Damle
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi - 110 029
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijnm.IJNM_147_19
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Graves' ophthalmopathy (GO) involves autoimmune activation of fibroblasts, resulting in chronic inflammatory reaction. Somatostatin receptors are expressed in the cells associated with chronic inflammation. We hereby present patients with active GO, with delayed response to the standard treatment regimen, in whom68Ga-DOTANOC positron emission tomography/computed tomography (PET/CT) was planned to evaluate the orbital inflammation.68Ga-DOTANOC PET/CT shows no physiological orbital muscle uptake. It can provide information which may possibly of utility in response assessment and also screening patients who fail to respond to conventional treatment, for newer therapies such as long-acting somatostatin analogs.
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