Indian Journal of Nuclear Medicine
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Year : 2021  |  Volume : 36  |  Issue : 1  |  Page : 100-102

Isolated Splenic tuberculosis masquerading as disease progression of hodgkin's lymphoma on interim18F-fluorodeoxyglucose positron emission tomography/computed tomography scan

1 Department of Nuclear Medicine, Mahajan Imaging, Sir Gangaram Hospital, New Delhi, India
2 Department of Pathology, Sir Ganga Ram Hospital, New Delhi, India

Correspondence Address:
Dr. Sudip Dey
Department of Nuclear Medicine, Sir Ganga Ram Hospital, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijnm.IJNM_145_20

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18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scan is the imaging modality of choice in the management of lymphoma. However, 18F-FDG is a nonspecific tracer for tumoral metabolic activity and infective pathology, thus posing a challenge in accurate response assessment. Here, we present a case of Hodgkin's lymphoma, referred for staging PET/CT scan which showed FDG-avid disease in the mediastinum, and on interim 18F-FDG PET/CT in addition to the mediastinal mass lesion, a FDG-avid lesion was also noted in the spleen suggestive of disease progression. The biopsy report of the lesion was tuberculosis, which was masquerading as disease progression on interim 18F-FDG PET/CT.

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