Indian Journal of Nuclear Medicine
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Year : 2021  |  Volume : 36  |  Issue : 3  |  Page : 346-347

Unusual case of neuroblastoma with only growth plate metastasis in bilateral lower limbs on metaiodobenzylguanidine scintigraphy

Department of Nuclear Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

Correspondence Address:
Dr. Sameer Taywade
Department of Nuclear Medicine, All India Institute of Medical Sciences, Basni Phase II, Jodhpur - 342 005, Rajasthan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijnm.ijnm_24_21

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Neuroblastoma is the most common extracranial solid tumor in childhood developing from primitive neural crest cells. I-131-metaiodobenzylguanidine (MIBG) a norepinephrine analog is highly sensitive and specific to identify primary and distant metastatic sites. We report the case of a 2-year-old female child with progressively increasing abdominal distention. Computed tomography (CT) revealed a large mass lesion involving the right suprarenal region with no hepatic or lymph node metastasis. No obvious skeletal abnormality was detected on the whole-body skeletal survey and Tc-99 m-methylene diphosphonate bone scan to suggest metastasis. I-131-MIBG scintigraphy with single-photon emission computerized tomography-CT showed MIBG-avid primary tumor in a suprarenal location with bilateral lower limbs growth plate as the only site of metastasis.

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