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| LETTER TO THE EDITOR |
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| Year : 2022 | Volume
: 37
| Issue : 2 | Page : 207 |
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Biological effects associated with internal and external contamination of diagnostic nuclear medicine sources: Correspondence
Pathum Sookaromdee1, Viroj Wiwanitkit2
1 Private Academic Consultant, Bangkok, Thailand
2 Department of Community Medicine, DY Patil University, Pune, Maharashtra, India
| Date of Submission | 25-Nov-2021 |
| Date of Decision | 28-Nov-2021 |
| Date of Acceptance | 30-Nov-2021 |
| Date of Web Publication | 08-Jul-2022 |
Correspondence Address:
Dr. Pathum Sookaromdee
Private Academic Consultant, 111 Bangkok, 122 Bangkok 103300
Thailand
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijnm.ijnm_186_21
How to cite this article:
Sookaromdee P, Wiwanitkit V. Biological effects associated with internal and external contamination of diagnostic nuclear medicine sources: Correspondence. Indian J Nucl Med 2022;37:207 |
How to cite this URL:
Sookaromdee P, Wiwanitkit V. Biological effects associated with internal and external contamination of diagnostic nuclear medicine sources: Correspondence. Indian J Nucl Med [serial online] 2022 [cited 2022 Aug 11];37:207. Available from: https://www.ijnm.in/text.asp?2022/37/2/207/350268 |
We would like to share ideas on “Biological effects associated with internal and external contamination of diagnostic nuclear medicine sources: An In vitro study.[1]” Elessawy et al. concluded that “Our in vitro study practically demonstrated that internal contamination is more hazardous than external exposure.[1]” and “DNA damages are directly associated with increasing irradiation time … contamination and related biological effects.[1]” We agree that internal exposure should be more problematic than external exposure. However, the present model might be difficult to represent an internal exposure due to its nature of in vitro and ex vivo study. All exposures in any group might be considered to get partial or total from external sources. Finally, the analytical technique, comet assay, is recognized as a highly variable investigation with the problem of reproducibility.[2] These factors should be recognized in interpretation of the present in vitro experiment.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
 References | |  |
| 1. | Nautiyal A, Mondal T, Goel A, Dey SK, Mitra D. Biological effects associated with internal and external contamination of diagnostic nuclear medicine sources: An in vitro study. Indian J Nucl Med 2021;36:288-92.  [Full text] |
| 2. | Azqueta A, Ladeira C, Giovannelli L, Boutet-Robinet E, Bonassi S, Neri M, et al. Application of the comet assay in human biomonitoring: An hCOMET perspective. Mutat Res Rev Mutat Res 2020;783:108288. |
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