Indian Journal of Nuclear Medicine
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INTERESTING IMAGE
Year : 2022  |  Volume : 37  |  Issue : 3  |  Page : 290-292

Multimodality molecular imaging in arthropathy associated with multiple myeloma


1 Department of Radiology, Division of Nuclear Medicine, Faculty of Medical Sciences, University of Campinas, São Paulo, Brazil
2 Department of Internal Medicine, Division of Hematology, Faculty of Medical Sciences, University of Campinas, São Paulo, Brazil
3 Department of Radiology, Faculty of Medical Sciences, University of Campinas, São Paulo, Brazil

Correspondence Address:
Prof. Celso Dario Ramos
Department of Radiology, Division of Nuclear Medicine, Faculty of Medical Sciences, University of Campinas, Zeferino Vaz Avenue, S/N. PO Box 6149, São Paulo
Brazil
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnm.ijnm_205_21

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We report a patient with multiple myeloma (MM) and polyarthritis of large joints. During the staging of the disease, bone marrow diffusely involved by MM was clearly demonstrated by 99mTc-2-methoxy-isobutyl-isonitrile (MIBI) single-photon emission computed tomography/computed tomography (SPECT/CT) but not by 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/CT images. On the other hand, a very intense uptake of 18F-FDG was detected in periarticular tissues of multiple joints, with nonabnormal 99mTc-MIBI accumulation. Rheumatology tests were negative. A subsequent bone scintigraphy demonstrated radiolabeled bisphosphonate accumulation in periarticular tissues, suggesting amyloid arthropathy.


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