Indian Journal of Nuclear Medicine
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Year : 2022  |  Volume : 37  |  Issue : 3  |  Page : 295-296

99mTc-ethambutol scan with SPECT/CT in knee joint tuberculosis


1 Department of Nuclear Medicine and PET-CT, All India Institute of Medical Sciences, New Delhi, India
2 Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
3 Department of Radiology, All India Institute of Medical Sciences, New Delhi, India
4 Department of Orthopedics, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Dr. Nishikant Avinash Damle
Department of Nuclear Medicine and PET-CT, All India Institute of Medical Sciences, New Delhi - 110 029
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnm.ijnm_16_22

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Modalities for in vivo imaging of Mycobacterium tuberculosis are limited and inadequately studied. One such modality is 99mTc-ethambutol scintigraphy which has shown promising results for diagnosis of tuberculosis (TB). Ethambutol, one of the primary antitubercular drugs, is bacteriostatic which acts on the mycolic acid cell wall synthesis of the M. tuberculosis. However, literature on its utility is scarce. The few studies that exist have reported its sensitivity and specificity between 90%– 95% and 71%–85%. We present here a case demonstrating the role of 99mTc-ethambutol scan in knee joint TB.


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