INTERESTING IMAGE |
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Year : 2023 | Volume
: 38
| Issue : 1 | Page : 65-66 |
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Intense fluorodeoxyglucose uptake in aggressive systemic mastocytosis without associated hematological neoplasm: Unusual fluorodeoxyglucose positron emission tomography/computed tomography presentation
Nosheen Fatima1, Areeba Zaman2, Sidra Zaman3, Unaiza Zaman4, Maseeh U Z. Zaman1
1 Department of Radiology, Aga Khan University Hospital, Karachi, Pakistan 2 Department of Medicine, Sunny Down State Hospital, New York, USA 3 Resident Medicine, Dr. Ruth Pfau Hospital, DUHS, Karachi, Pakistan 4 Fellow Haem-Oncology, Oklahoma University, Oklahoma, USA
Correspondence Address:
Prof. Maseeh U Z. Zaman Department of Radiology, Aga Khan University Hospital, Karachi Pakistan
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijnm.ijnm_88_22
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Systemic mastocytosis (SM) is a relatively rare heterogeneous group of disorders characterized by uncontrolled proliferation and accumulation of clonal mast cells in one or more organs. Indolent SM is the most common variety. Less common variety is aggressive systemic mastocytosis (aSM) type with or without associated hematological neopalsm (AHN). Fludeoxyglucose (FDG) positron emission tomography/computed tomography has a limited role in aSM without AHN as these exhibit low FDG avidity. We are presenting a biopsy-proven case of aSM without AHN showing abnormally high FDG uptake in lesions involving skin, nodes, marrow, and muscles.
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