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Year : 2023 | Volume
: 38
| Issue : 1 | Page : 79-80 |
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Malignancy-Associated sarcoid-like reaction in a case of triple-negative breast cancer on F-18 fluorodeoxyglucose positron emission tomography/computed tomography
Sneha Prakash1, Nishikant Avinash Damle1, Karan Madan2, Prashant Ramteke3
1 Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India 2 Department of Pulmonary Medicine, All India Institute of Medical Sciences, New Delhi, India 3 Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
Correspondence Address:
Dr. Nishikant Avinash Damle Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi - 110 029 India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijnm.ijnm_130_22
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We describe the case of a 54-year-old woman with triple-negative breast cancer whose baseline F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) showed hypermetabolic left breast primary, ipsilateral axillary lymphadenopathy, lung nodules, and mediastinal lymph nodes. Histopathological examination of tissue from mediastinal lymph nodes confirmed a diagnosis of sarcoid-like reaction. Chemotherapy may induce or cause a flare-up of malignancy-associated sarcoid-like reaction. However, in our patient's post-chemotherapy F-18 FDG PET/CT, there was reduction in size and uptake of the mediastinal lymph nodes along with partial response shown by the other lesions. We aim to describe this rare course of malignancy-associated sarcoid-like reaction and highlight the role of F-18 FDG PET-CT in such cases.
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